• HOME
  • RESEARCH
  • PEOPLE
    • JOIN US
  • PUBLICATIONS
  • FRIENDS
  • SUPPORT US
  • NEWS
  • CONTACT
Lohr Lab - Precision Hematology/Oncology

Lohr Lab
PRECISION HEMATOLOGY/ONCOLOGY

Welcome to Lohr Lab

The Lohr lab explores tumor evolution and drug resistance in various types of cancer, with a particular interest in multiple myeloma. We use "liquid biopsy" approaches to obtain circulating tumor cells (CTCs) and cell-free DNA (cfDNA) combined with innovative DNA- and RNA-sequencing technologies and computational analysis, as tools to gain insight into tumor biology and translate these findings into novel targeted therapies.
​
These strategies yield potential targets that may be exploited for overcoming drug resistance. For mechanistic exploration of these candidate targets we use a wide variety of tools, which span the spectrum from biochemistry to mouse models. These approaches will lead to a better understanding of the dynamic molecular and genetic changes of cancer over time, which will be crucial for effective precision medicine.
 

​

Picture
Picture
 HOME | RESEARCH| PEOPLE | PUBLICATIONS | FRIENDS | NEWS | SUPPORT US | CONTACT
©2016 Precision Hematology/Oncology at Dana-Farber Cancer Institute